The Ross Group

Grenade, N.L., Chiriac, D.S., Pasternak, A.R.O., Babulic, J.L., Rowland, B.E., Howe, G.W., Ross, A.C., Discovery of a Tambjamine Gene Cluster in Streptomyces Suggests Convergent Evolution in Bipyrrole Natural Product Biosynthesis, ACS Chem. Bio., 2023, 18(2), 223-229 DOI: 10.1021/acschembio.2c00685

Hermann, M., Metwally, H., Yu, J., Smith, R., Tomm, H., Kaufmann, M., Ren, K.Y.M., Liu, C., LeBlanc, Y., Covey, T.R., Ross, A.C., Oleschuk, R.D., 3D printer platform and conductance feedback loop for automated imaging of uneven surfaces by liquid microjunction-surface sampling probe mass spectrometry, Rapid Commun. Mass Spectrom., 2023 DOI: 10.1002/rcm.9492

Moran, M.A., Kujawinski, E.B., Schroer, W.F., Amin, S.A., Bates, N.R., Bertrand, E.M., Braakman, R., Brown, C.T., Covert, M.W., Doney, S.C., Dyhrman, S.T., Edison, A.S., Eren, A.M., Levine, N.M., Li, L., Ross, A.C., Saito, M.A., Santoro, A.E., Segrè, D., Shade, A., Sullivan, M.B., Vardi, A., Microbial metabolites in the marine carbon cycle, Nat. Microb., 2022, 7(4), 508-523 DOI: 10.1038/s41564-022-01090-3

Yu, J., Hermann, M., Smith, R., Tomm, H., Metwally, H., Kolwich, J., Liu, C., Le Blanc, J.C.Y., Covey, T.R., Ross, A.C., Oleschuk, R., Hyperspectral Visualization-Based Mass Spectrometry Imaging by LMJ-SSP: A Novel Strategy for Rapid Natural Product Profiling in Bacteria, Anal. Chem., 2022 DOI: 10.1021/acs.analchem.2c04550

Grenade, N. L., Howe, G. W., Ross, A. C., The convergence of bacterial natural products from evolutionarily distinct pathways, Curr. Opin. Biotech., 2021, 69, 17-25 DOI: 10.1016/j.copbio.2020.10.009 (Invited for special Issue “Pharmaceutical Biotechnology 2021”)

Deichert, J. A., Mizufune, H., Patel, J., Hurst, T. E., Maheta, A., Kitching, M. O., Ross, A. C., Snieckus, V., Expedient Pd‐catalyzed α‐arylation towards dibenzoxepinones: Pivotal Manske’s ketone for the formal synthesis of cularine alkaloids, Eur. J. Org. Chem., 2020, 4693-4697 DOI: 10.1002/ejoc.202000424

Timmermans, M. L., Ross, A. C., Unearthing Hidden Chemical Potential from Discarded Actinobacterial Libraries, Trends Biotechnol., 2020, 38, 7-9 DOI: 10.1016/j.tibtech.2019.11.003 (This is an invited contribution)

Picott, K. J., Deichert, J. A., Dekemp, E. M., Snieckus, V., Ross, A. C., Purification and kinetic characterization of the essential condensation enzymes involved in prodiginine and tambjamine biosynthesis, ChemBioChem, 2020, 21, 1036-1042 DOI: 10.1002/cbic.201900503

Zhang, J. J., Tang, X., Huan, T., Ross, A. C., Moore, B. S., Pass-back chain extension expands multi-modular assembly line biosynthesis, Nat. Chem. Biol., 2020, 16, 42-49 DOI: 10.1038/s41589-019-0385-4

Tomm, H. A., Ucciferri, L., Ross, A. C., Advances in microbial culturing conditions to activate silent biosynthetic gene clusters for novel metabolite production J. Ind. Microbiol. Biotech., 2019, 46, 1381-1400 DOI: 10.1007/s10295-019-02198-y (Invited for special Issue “Frontiers of Industrial Microbiology and Biotechnology: SIMB‐2018”)

Agrawal, P., Salomons, T. T., Chiriac, D. S., Ross, A. C., Oleschuk, R. D., Facile actuation of organic and aqueous droplets on slippery liquid infused porous surfaces for the application of on-chip polymer synthesis and liquid-liquid extraction, ACS Appl. Mater. Interfaces, 2019, 11, 28327-28335 DOI: 10.1021/acsami.9b08849

Picott, K. J., Deichert, J. A., Schatte, G., Sauriol, F., Ross, A. C., Isolation and characterization of tambjamine MYP1, a macrocyclic tambjamine analogue from marine bacterium Pseudoalteromonas citrea, MedChemComm, 2019, 10, 478-483 DOI: 10.1039/c9md00061e (Invited for special Natural Products Issue)

Timmermans, M. L., Picott, K. J., Ucciferri, L., Ross, A. C. , Culturing marine bacteria from the genus Pseudoalteromonas on a cotton scaffold activates silent biosynthetic pathways and alters secondary metabolite production, MicrobiologyOpen, 2018, e724 DOI: 10.1002/mbo3.724

Timmermans, M. L., Paudel, Y. P., Ross, A. C., Investigating the Biosynthesis of Natural Products from Marine Proteobacteria: A Survey of Molecules and Strategies, Mar. Drugs, 2017, 15, 235 DOI: 10.3390/md15080235  (Invited Review and Front Cover)

Zhang, W., Lu, L., Lai, Q., Zhu, B., Li, Z., Xu, Y., Shao, Z., Herrup, K., Moore, B. S., Ross, A. C., Qian, P.-Y., Family-wide Structural Characterization and Genomic Comparisons Decode the Diversity-oriented Biosynthesis of Thalassospiramides by Marine Proteobacteria, J. Biol. Chem., 2016, 291, 27228-27238. (Highlighted in ASBMB Today, March 2017, vol 16, Issue 3, pg 15) DOI: 10.1074/jbc.M116.756858

Ross, A. C., Gulland, L., Dorrestein, P. C., Moore, B. S., Targeted Capture and Heterologous Expression of the Pseudoalteromonas Bromoalterochromide Gene Cluster in Escherichia coli Represents a Promising Natural Product Exploratory Platform, ACS Syn. Biol., 2015, 4, 414-420.

Ross, A. C., Xu, Y., Lu, L., Kersten, R. D., Shao, Z., Al-Suwailem, A. M., Dorrestein, P. C., Qian, P.-Y., Moore, B. S., Biosynthetic Multitasking Facilitates Thalassospiramide Structural Diversity in Marine Bacteria, J. Am. Chem. Soc., 2013, 135, 1155-1162.

McKinnie, S. M. K., Ross, A. C., Little, M. J., Vederas, J. C., The Solid Phase Supported Peptide Synthesis of Analogues of the Lantibiotic Lactocin S, MedChemComm, 2012, 3, 971-975.

Ross, A. C., McKinnie, S. M. K., Vederas, J. C., The Synthesis of Active and Stable Diaminopimelate Analogues of the Lantibiotic Peptide Lactocin S, J. Am. Chem. Soc., 2012, 134, 2008-2011.

Shaheen, M., Li, J., Ross, A. C., Vederas, J. C., Jensen, S., Paenibacillus polymyxa PKBI produces Novel Variants of Polymyxin B-type Antibiotics, Chem. Biol., 2011, 18, 1640-1648.

Ross, A. C., Vederas, J. C., Fundamental Functionality – Recent Developments in Understanding the Structure Activity Relationships of Lantibiotic Peptides, J. Antibiot., 2011, 64, 27-34.

Ross, A. C., Liu, H., Pattabiraman, V. R., Vederas, J. C., Synthesis of the Lantibiotic Lactocin S Using Peptide Cyclizations on Solid Phase, J. Am. Chem. Soc., 2010, 132, 462-463.

Wood, T. E., Ross, A. C., Dalgleish, N. D., Power, E.D., Thompson, A., Chen, X., Okamoto, Y., Dinuclear Zinc(II) Double-Helicates of Homochirally Substituted Bis(dipyrromethene)s, J. Org. Chem., 2005, 70, 9967-9974.